Folic acid relieves bone cancer pain by downregulating P2X2/3 receptors in rats.

Gu, Yong-Juan; Qian, He-Ya; Zhou, Fang; Zhang, Ling; Chen, Long; Song, Yu; Chen, Ya-Nan; Zhang, Hai-Long

Gu, Yong-Juan; Qian, He-Ya; Zhou, Fang; Zhang, Ling; Chen, Long; Song, Yu; Chen, Ya-Nan; Zhang, Hai-Long.

Afiliação

Gu YJ; Center for Translational Medicine, The Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China; Department of Oncology, The Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China.
Qian HY; Center for Translational Medicine, The Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China; Department of Oncology, The Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China.
Zhou F; Center for Translational Medicine, The Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China; Department of Oncology, The Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China.
Zhang L; Center for Translational Medicine, The Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China.
Chen L; Center for Translational Medicine, The Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China.
Song Y; Department of Oncology, The Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China.
Chen YN; Department of Oncology, The Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China. Electronic address: chenyanan99@126.com.
Zhang HL; Center for Translational Medicine, The Affiliated Zhangjiagang Hospital of Soochow University, Zhangjiagang 215600, China; Jiangsu Key Laboratory of Neuropsychiatric Diseases, Institute of Neuroscience, Soochow University, Suzhou 215123, China. Electronic address: hlzhang76@suda.edu.cn.

Brain Res ; 1811: 148405, 2023 07 15.

Article em En | MEDLINE | ID: mdl-37164174

Assuntos

Neoplasias Ósseas; Dor do Câncer; Neuralgia; Ratos; Animais; Dor do Câncer/metabolismo; Ratos Sprague-Dawley; Ácido Fólico/farmacologia; Ácido Fólico/metabolismo; Ácido Fólico/uso terapêutico; Neuralgia/metabolismo; Neoplasias Ósseas/patologia; Analgésicos/farmacologia; Analgésicos/uso terapêutico; RNA Mensageiro/metabolismo; Gânglios Espinais/metabolismo; Hiperalgesia/metabolismo

Palavras-chave

Bone cancer pain; DRG; Folic acid; P2X2/3 receptors; SDH

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ósseas / Dor do Câncer / Neuralgia Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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