Resveratrol exhibits diverse anti-cancer activities through epigenetic regulation of E-cadherin and p21 in triple-negative breast cancer cells.

Sakamoto, Takako; Tanimoto, Keiji; Eguchi, Hidetaka; Sasaki, Shunta; Tsuboi, Kouki; Hayashi, Shin-Ichi; Ichihara, Sahoko

Sakamoto, Takako; Tanimoto, Keiji; Eguchi, Hidetaka; Sasaki, Shunta; Tsuboi, Kouki; Hayashi, Shin-Ichi; Ichihara, Sahoko.

Afiliação

Sakamoto T; Department of Environmental and Preventive Medicine, School of Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan. takakos@jichi.ac.jp.
Tanimoto K; Department of Radiation Disaster Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima-shi, Hiroshima, 734-8553, Japan.
Eguchi H; Diagnostics and Therapeutics of Intractable Diseases and Intractable Disease Research Center, Juntendo University Graduate School of Medicine, Bunkyo-ku, Tokyo, 113-8421, Japan.
Sasaki S; Department of Molecular and Functional Dynamics, Graduate School of Medicine, Tohoku University, Sendai-shi, Miyagi, 980-8575, Japan.
Tsuboi K; Department of Molecular and Functional Dynamics, Graduate School of Medicine, Tohoku University, Sendai-shi, Miyagi, 980-8575, Japan.
Hayashi SI; Department of Molecular and Functional Dynamics, Graduate School of Medicine, Tohoku University, Sendai-shi, Miyagi, 980-8575, Japan.
Ichihara S; Department of Environmental and Preventive Medicine, School of Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.

Breast Cancer ; 30(5): 727-738, 2023 Sep.

Article em En | MEDLINE | ID: mdl-37166625

Assuntos

Antineoplásicos; Neoplasias de Mama Triplo Negativas; Humanos; Resveratrol/farmacologia; Resveratrol/uso terapêutico; Neoplasias de Mama Triplo Negativas/tratamento farmacológico; Neoplasias de Mama Triplo Negativas/genética; Neoplasias de Mama Triplo Negativas/patologia; Proteína BRCA1/genética; Proteína BRCA1/metabolismo; Histonas/genética; Histonas/metabolismo; Histonas/farmacologia; Proliferação de Células; Epigênese Genética; Linhagem Celular Tumoral; Proteína BRCA2/genética; Antineoplásicos/uso terapêutico; Apoptose; Caderinas/genética; Caderinas/metabolismo

Palavras-chave

ABT263; E-cadherin; Resveratrol; Triple-negative breast cancer; p21

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias de Mama Triplo Negativas / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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