Palladium-Catalyzed Synthesis of Cyclopropylthiophenes and Their Derivatization.
Molecules
; 28(9)2023 Apr 27.
Article
em En
| MEDLINE
| ID: mdl-37175178
ABSTRACT
The cyclopropylthiophene moiety has attracted the attention of the scientific community for its potential pharmaceutical applications. However, synthesis of the compounds containing this framework remains challenging, has rarely been reported and remains unresolved. Here we provide optimized syntheses for cyclopropylthiophenes and their derivatives, containing carbonyl, acetyl, carboxylic acid, methyl carboxylate, nitrile, bromide and sulfonyl chloride moieties.
Texto completo:
1
Base de dados:
MEDLINE
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article