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Novel multi-target ligands of dopamine and serotonin receptors for the treatment of schizophrenia based on indazole and piperazine scaffolds-synthesis, biological activity, and structural evaluation.
Stepnicki, Piotr; Wronikowska-Denysiuk, Olga; Zieba, Agata; Targowska-Duda, Katarzyna M; Bartyzel, Agata; Wróbel, Martyna Z; Wróbel, Tomasz M; Szalaj, Klaudia; Chodkowski, Andrzej; Mirecka, Karolina; Budzynska, Barbara; Fornal, Emilia; Turlo, Jadwiga; Castro, Marián; Kaczor, Agnieszka A.
Afiliação
  • Stepnicki P; Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy, Medical University of Lublin, Lublin, Poland.
  • Wronikowska-Denysiuk O; Independent Laboratory of Behavioral Studies, Chair of Biomedical Sciences, Faculty of Biomedicine, Medical University of Lublin, Lublin, Poland.
  • Zieba A; Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy, Medical University of Lublin, Lublin, Poland.
  • Targowska-Duda KM; Department of Biopharmacy, Faculty of Pharmacy, Medical University of Lublin, Lublin, Poland.
  • Bartyzel A; Department of General and Coordination Chemistry and Crystallography, Institute of Chemical Sciences, Faculty of Chemistry, Maria Curie-Sklodowska University in Lublin, Lublin, Poland.
  • Wróbel MZ; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
  • Wróbel TM; Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy, Medical University of Lublin, Lublin, Poland.
  • Szalaj K; Department of Bioanalytics, Faculty of Biomedicine, Medical University of Lublin, Lublin, Poland.
  • Chodkowski A; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
  • Mirecka K; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
  • Budzynska B; Independent Laboratory of Behavioral Studies, Chair of Biomedical Sciences, Faculty of Biomedicine, Medical University of Lublin, Lublin, Poland.
  • Fornal E; Department of Bioanalytics, Faculty of Biomedicine, Medical University of Lublin, Lublin, Poland.
  • Turlo J; Department of Drug Technology and Pharmaceutical Biotechnology, Faculty of Pharmacy, Medical University of Warsaw, Warsaw, Poland.
  • Castro M; Department of Pharmacology, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain.
  • Kaczor AA; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain.
J Enzyme Inhib Med Chem ; 38(1): 2209828, 2023 Dec.
Article em En | MEDLINE | ID: mdl-37184096
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esquizofrenia / Antipsicóticos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esquizofrenia / Antipsicóticos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article