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FDA-approved carbonic anhydrase inhibitors reduce amyloid ß pathology and improve cognition, by ameliorating cerebrovascular health and glial fitness.
Canepa, Elisa; Parodi-Rullan, Rebecca; Vazquez-Torres, Rafael; Gamallo-Lana, Begona; Guzman-Hernandez, Roberto; Lemon, Nicole L; Angiulli, Federica; Debure, Ludovic; Ilies, Marc A; Østergaard, Leif; Wisniewski, Thomas; Gutiérrez-Jiménez, Eugenio; Mar, Adam C; Fossati, Silvia.
Afiliação
  • Canepa E; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
  • Parodi-Rullan R; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
  • Vazquez-Torres R; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
  • Gamallo-Lana B; Department of Neuroscience and Physiology, Neuroscience Institute, NYU Grossman School of Medicine, New York, New York, USA.
  • Guzman-Hernandez R; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
  • Lemon NL; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
  • Angiulli F; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
  • Debure L; Department on Neurology, Center for Cognitive Neurology, NYU Grossman School of Medicine, New York, New York, USA.
  • Ilies MA; Department of Pharmaceutical Sciences and Moulder Center for Drug Discovery Research, Temple University School of Pharmacy, Temple University, Philadelphia, Pennsylvania, USA.
  • Østergaard L; Center of Functionally Integrative Neuroscience (CFIN), Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Wisniewski T; Department on Neurology, Center for Cognitive Neurology, NYU Grossman School of Medicine, New York, New York, USA.
  • Gutiérrez-Jiménez E; Center of Functionally Integrative Neuroscience (CFIN), Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Mar AC; Department of Neuroscience and Physiology, Neuroscience Institute, NYU Grossman School of Medicine, New York, New York, USA.
  • Fossati S; Alzheimer's Center at Temple, Department of Neural Sciences, Lewis Katz School of Medicine, Temple University, Philadelphia, Pennsylvania, USA.
Alzheimers Dement ; 19(11): 5048-5073, 2023 11.
Article em En | MEDLINE | ID: mdl-37186121

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Angiopatia Amiloide Cerebral / Doença de Alzheimer Limite: Animals / Humans País como assunto: America do norte Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Angiopatia Amiloide Cerebral / Doença de Alzheimer Limite: Animals / Humans País como assunto: America do norte Idioma: En Ano de publicação: 2023 Tipo de documento: Article