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BRSK2 in pancreatic ß cells promotes hyperinsulinemia-coupled insulin resistance and its genetic variants are associated with human type 2 diabetes.
Xu, Rufeng; Wang, Kaiyuan; Yao, Zhengjian; Zhang, Yan; Jin, Li; Pang, Jing; Zhou, Yuncai; Wang, Kai; Liu, Dechen; Zhang, Yaqin; Sun, Peng; Wang, Fuqiang; Chang, Xiaoai; Liu, Tengli; Wang, Shusen; Zhang, Yalin; Lin, Shuyong; Hu, Cheng; Zhu, Yunxia; Han, Xiao.
Afiliação
  • Xu R; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China.
  • Wang K; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China.
  • Yao Z; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China.
  • Zhang Y; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China.
  • Jin L; Institute for Metabolic Disease, Fengxian Central Hospital Affiliated to Southern Medical University, Shanghai 201499, China.
  • Pang J; Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
  • Zhou Y; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China.
  • Wang K; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China.
  • Liu D; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China.
  • Zhang Y; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China.
  • Sun P; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China.
  • Wang F; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China.
  • Chang X; Analysis Center, Nanjing Medical University, Nanjing 210029, China.
  • Liu T; Key Laboratory of Human Functional Genomics of Jiangsu Province, Nanjing Medical University, Nanjing 211166, China.
  • Wang S; Organ Transplant Center, Tianjin First Central Hospital, Nankai University, Tianjin 300192, China.
  • Zhang Y; Organ Transplant Center, Tianjin First Central Hospital, Nankai University, Tianjin 300192, China.
  • Lin S; State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen 361102, China.
  • Hu C; State Key Laboratory for Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen 361102, China.
  • Zhu Y; Institute for Metabolic Disease, Fengxian Central Hospital Affiliated to Southern Medical University, Shanghai 201499, China.
  • Han X; Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Clinical Center for Diabetes, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China.
J Mol Cell Biol ; 15(5)2023 Nov 27.
Article em En | MEDLINE | ID: mdl-37188647
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Hiperinsulinismo Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Diabetes Mellitus Tipo 2 / Células Secretoras de Insulina / Hiperinsulinismo Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article