Transcriptomic responses of peripheral blood mononuclear cells to cyclosporin and etanercept in a female infant with juvenile generalized pustular psoriasis.

Lin, Yu-Chen; Jeng, Yu-Chen; Aala, Wilson Jr F; Hong, Yi-Kai; Chen, Pin-Hsuan; Chuang, Ya-Ru; Yang, Chao-Chun; Hsu, Chao-Kai

Lin, Yu-Chen; Jeng, Yu-Chen; Aala, Wilson Jr F; Hong, Yi-Kai; Chen, Pin-Hsuan; Chuang, Ya-Ru; Yang, Chao-Chun; Hsu, Chao-Kai.

Afiliação

Lin YC; Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Jeng YC; International Center for Wound Repair and Regeneration (iWRR), National Cheng Kung University, Tainan, Taiwan.
Aala WJF; Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Hong YK; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chen PH; Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Chuang YR; International Center for Wound Repair and Regeneration (iWRR), National Cheng Kung University, Tainan, Taiwan.
Yang CC; Department of Dermatology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Hsu CK; School of Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Exp Dermatol ; 32(8): 1299-1305, 2023 08.

Article em En | MEDLINE | ID: mdl-37194367

Assuntos

Ciclosporina; Psoríase; Humanos; Feminino; Lactente; Etanercepte/farmacologia; Etanercepte/uso terapêutico; Ciclosporina/uso terapêutico; Transcriptoma; Interleucinas/genética; Leucócitos Mononucleares; Inibidores do Fator de Necrose Tumoral/uso terapêutico; Psoríase/tratamento farmacológico; Psoríase/genética; Doença Aguda; Doença Crônica; Guanilato Ciclase/genética; Proteínas de Membrana/genética; Proteínas Adaptadoras de Sinalização CARD/genética

Palavras-chave

RNA sequencing; TNF-alpha inhibitor; cyclosporin; etanercept; general pustular psoriasis; transcriptome; whole-exome sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Psoríase / Ciclosporina Tipo de estudo: Prognostic_studies Limite: Female / Humans / Infant Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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