Bimetallic Ions Functionalized Metal-Organic-Framework Nanozyme for Tumor Microenvironment Regulating and Enhanced Photodynamic Therapy for Hypoxic Tumor.

Pan, Meng-Meng; Li, Puze; Yu, Yan-Ping; Jiang, Ming; Yang, Xiangliang; Zhang, Pei; Nie, Jing; Hu, Jun; Yu, Xu; Xu, Li

Pan, Meng-Meng; Li, Puze; Yu, Yan-Ping; Jiang, Ming; Yang, Xiangliang; Zhang, Pei; Nie, Jing; Hu, Jun; Yu, Xu; Xu, Li.

Afiliação

Pan MM; Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Li P; National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China.
Yu YP; Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Jiang M; Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.
Yang X; National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China.
Zhang P; Wuhan Institute of Virology, CAS, Wuhan, 430071, China.
Nie J; Hubei Medical Devices Quality Supervision and Test Institute, High-Tech Avenue 507#, Wuhan, 430075, China.
Hu J; National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China.
Yu X; Hubei Jiangxia Laboratory, Wuhan, 430200, China.
Xu L; Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan, 430030, China.

Adv Healthc Mater ; 12(26): e2300821, 2023 10.

Article em En | MEDLINE | ID: mdl-37199497

Assuntos

Estruturas Metalorgânicas; Nanopartículas; Neoplasias; Fotoquimioterapia; Humanos; Fármacos Fotossensibilizantes/farmacologia; Fármacos Fotossensibilizantes/uso terapêutico; Fotoquimioterapia/métodos; Espécies Reativas de Oxigênio; Microambiente Tumoral; Neoplasias/tratamento farmacológico; Hipóxia/tratamento farmacológico; Linhagem Celular Tumoral; Peróxido de Hidrogênio/farmacologia

Palavras-chave

bimetallic ions; hypoxia relief; metal-organic-frameworks; nanozymes; photodynamic therapy; tumor microenvironment regulation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fotoquimioterapia / Nanopartículas / Estruturas Metalorgânicas / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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