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Invasive Aspergillosis in a Patient With Diabetes Mellitus as the Only Risk Factor: Case Report and Literature Review.
Fernández-Trujillo, Liliana; Eraso, Isabel; Morales, Eliana I; Sua, Luz F.
Afiliação
  • Fernández-Trujillo L; Fundación Valle del Lili, Cali, Colombia.
  • Eraso I; Universidad Icesi, Cali, Colombia.
  • Morales EI; Fundación Valle del Lili, Cali, Colombia.
  • Sua LF; Universidad Icesi, Cali, Colombia.
J Investig Med High Impact Case Rep ; 11: 23247096231175443, 2023.
Article em En | MEDLINE | ID: mdl-37203376
ABSTRACT
Infection by Aspergillus covers a broad clinical spectrum, including invasive pulmonary aspergillosis (IPA) and its disseminated extrapulmonary form, invasive aspergillosis (IA). It typically occurs in severely immunocompromised hosts, but it sometimes affects the immunocompetent population, especially patients with acute diseases being treated at the intensive care unit (ICU) and less often those with chronic conditions. In this article, we report the case of a 50-year-old male, with diabetes mellitus (DM) as the only risk factor, treated for IPA and IA with cardiac and central nervous system (CNS) involvement at a high complexity institution in Cali-Colombia. Clinical presentation and radiological findings are unspecific and require a high level of suspicion. To confirm the case, histological or cytological of the fungus is required; histopathological examination of lung tissue is the gold standard, but it is difficult to perform due to respiratory compromise and high risk of bleeding, so bronchoscopy and bronchoalveolar lavage (BAL) plays an essential role in the diagnostic process. A diagnostic algorithm that includes risk assessment, symptoms, imaging findings, and isolation in cultures is essential to allow the diagnosis and initiation of treatment promptly, which includes a combination of surgery and antifungal medications for long periods, even life-long treatment.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aspergilose / Diabetes Mellitus / Aspergilose Pulmonar Invasiva Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Aspergilose / Diabetes Mellitus / Aspergilose Pulmonar Invasiva Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article