Genetic Evolution of Hepatitis E Virus.
Adv Exp Med Biol
; 1417: 59-72, 2023.
Article
em En
| MEDLINE
| ID: mdl-37223859
ABSTRACT
Comparative analysis of the genomic sequences of multiple hepatitis E virus (HEV) isolates has revealed extensive genomic diversity among them. Recently, a variety of genetically distinct HEV variants have also been isolated and identified from large numbers of animal species, including birds, rabbits, rats, ferrets, bats, cutthroat trout, and camels, among others. Furthermore, it has been reported that recombination in HEV genomes takes place in animals and in human patients. Also, chronic HEV infection in immunocompromised individuals has revealed the presence of viral strains carrying insertions from human genes. This paper reviews current knowledge on the genomic variability and evolution of HEV.
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Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Vírus da Hepatite E
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article