Exploring BenzylethoxyAryl Urea Scaffolds for Multitarget Immunomodulation Therapies.

Gil-Edo, Raquel; Hernández-Ribelles, German; Royo, Santiago; Thawait, Natasha; Serrels, Alan; Carda, Miguel; Falomir, Eva

Gil-Edo, Raquel; Hernández-Ribelles, German; Royo, Santiago; Thawait, Natasha; Serrels, Alan; Carda, Miguel; Falomir, Eva.

Afiliação

Gil-Edo R; Inorganic and Organic Chemistry Department, University Jaume I, 12071 Castellón, Spain.
Hernández-Ribelles G; Curapath, Benjamin Franklin Avenue 19, 46980 Paterna, Spain.
Royo S; Institute of Agronomic Engineering for Development, Polytechnic University of Valencia, 46022 Valencia, Spain.
Thawait N; Cancer Research UK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK.
Serrels A; Cancer Research UK Scotland Centre, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK.
Carda M; Inorganic and Organic Chemistry Department, University Jaume I, 12071 Castellón, Spain.
Falomir E; Inorganic and Organic Chemistry Department, University Jaume I, 12071 Castellón, Spain.

Int J Mol Sci ; 24(10)2023 May 11.

Article em En | MEDLINE | ID: mdl-37239929

Assuntos

Neoplasias; Ureia; Humanos; Ureia/farmacologia; Células HEK293; Proliferação de Células; Neoplasias/tratamento farmacológico; Imunomodulação; Linhagem Celular Tumoral

Palavras-chave

CD11b; CD69; CD8+ T cell; Fyn; LAG-3; LAT; LCK; OX-40; PD-1; PD-L1; TIM-3; TLCRs; VEGFR-2; ZAP70; angiogenesis; aryl urea; benzylethoxyaryl urea; immune checkpoints

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ureia / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ureia / Neoplasias Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article