Exosomes Derived from Adipose Tissue-Derived Mesenchymal Stromal Cells Prevent Medication-Related Osteonecrosis of the Jaw through IL-1RA.

Zheng, Yi; Dong, Xian; Wang, Xinyu; Wang, Jie; Chen, Shuo; He, Yang; An, Jingang; He, Linhai; Zhang, Yi

Zheng, Yi; Dong, Xian; Wang, Xinyu; Wang, Jie; Chen, Shuo; He, Yang; An, Jingang; He, Linhai; Zhang, Yi.

Afiliação

Zheng Y; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Dong X; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Wang X; First Clinical Division, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Wang J; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Chen S; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
He Y; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
An J; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
He L; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
Zhang Y; Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.

Int J Mol Sci ; 24(10)2023 May 12.

Article em En | MEDLINE | ID: mdl-37240036

Assuntos

Exossomos; Células-Tronco Mesenquimais; Osteonecrose; Camundongos; Animais; Humanos; Ácido Zoledrônico; Proteína Antagonista do Receptor de Interleucina 1/genética; Proteína Antagonista do Receptor de Interleucina 1/metabolismo; Exossomos/metabolismo; Microtomografia por Raio-X; Osteonecrose/metabolismo; Células-Tronco Mesenquimais/metabolismo; Colágeno/metabolismo

Palavras-chave

adipose tissue-derived mesenchymal stromal cells; exosomes; human gingival fibroblasts; interleukin-1 receptor antagonist; medication-related osteonecrosis of the jaw; primary wound healing; zoledronate

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osteonecrose / Exossomos / Células-Tronco Mesenquimais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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