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Befotertinib (D-0316) versus icotinib as first-line therapy for patients with EGFR-mutated locally advanced or metastatic non-small-cell lung cancer: a multicentre, open-label, randomised phase 3 study.
Lu, Shun; Zhou, Jianying; Jian, Hong; Wu, Lin; Cheng, Ying; Fan, Yun; Fang, Jian; Chen, Gongyan; Zhang, Zhihong; Lv, Dongqing; Jiang, Liyan; Wu, Rong; Jin, Xiangming; Zhang, Xiaodong; Zhang, Junhong; Xie, Conghua; Sun, Gengyun; Huang, Dongning; Cui, Jiuwei; Guo, Renhua; Han, Zhigang; Chen, Zhendong; Liang, Jin; Zhuang, Wu; Hu, Xingsheng; Zang, Aimin; Zhang, Yi; Cang, Shundong; Lan, Yuanbo; Chen, Xi; Liu, Laiyu; Li, Xingya; Chen, Jun; Ma, Rui; Guo, Yanzhen; Sun, Ping; Tian, Panwen; Pan, Yueyin; Liu, Zhe; Cao, Peiguo; Ding, Lieming; Wang, Yang; Yuan, Xiaobin; Wu, Pengxiang.
Afiliação
  • Lu S; Department of Medical Oncology, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. Electronic address: shunlu@sjtu.edu.cn.
  • Zhou J; Department of Respiratory Medicine, First Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China. Electronic address: zjyhz@zju.edu.cn.
  • Jian H; Department of Medical Oncology, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Wu L; Department of Thoracic Medical Oncology II, Hunan Cancer Hospital (The Affiliated Cancer Hospital of Xiangya School of Medicine), Central South University, Changsha, China.
  • Cheng Y; Department of Oncology, Jilin Cancer Hospital, Changchun, China.
  • Fan Y; Department of Thoracic Medical Oncology II, Cancer Hospital of the University of Chinese Academy of Sciences, Zhejiang Cancer Hospital, Hangzhou, China.
  • Fang J; Department of Thoracic Surgery, Beijing Cancer Hospital, Beijing, China.
  • Chen G; Department of Respiratory Medical Oncology, Harbin Medical University Affiliated Cancer Hospital, Harbin, China.
  • Zhang Z; Department of Respiratory Medicine, Anhui Provincial Cancer Hospital, Hefei, China.
  • Lv D; Breath Internal Medicine, Taizhou Hospital of Zhejiang Province, Linhai, China.
  • Jiang L; Department of Respiratory Medicine, Shanghai Chest Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Wu R; Second Oncology Ward, Shengjing Hospital of China Medical University, Shenyang, China.
  • Jin X; Department of Oncology, General Hospital of Ningxia Medical University, Yinchuan, China.
  • Zhang X; Department of Internal Medicine-Oncology, Nantong Tumor Hospital, Nantong, China.
  • Zhang J; Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Xie C; Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Sun G; Department of Respiratory Medicine, First Affiliated Hospital of Anhui Medical University, Hefei, China.
  • Huang D; Department of Medical Oncology, Liuzhou Workers' Hospital, Liuzhou, China.
  • Cui J; Department of Oncology, First Hospital of Jilin University, Changchun, China.
  • Guo R; Department of Oncology, Jiangsu Province Hospital (First Affiliated Hospital of Nanjing Medical University), Nanjing, China.
  • Han Z; Department of Pulmonary Medicine, 3rd Affiliated Teaching Hospital of Xinjiang Medical University (Affiliated Cancer Hospital), Urumqi, China.
  • Chen Z; Department of Medical Oncology, Second Hospital of Anhui Medical University, Hefei, China.
  • Liang J; Department of Medical Oncology, First Affiliated Hospital of Kunming Medical University, Kunming, China.
  • Zhuang W; Department of Thoracic Medical Oncology, Fujian Cancer Hospital, Fuzhou, China.
  • Hu X; Department of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
  • Zang A; Department of Medical Oncology, Affiliated Hospital of Hebei University, Baoding, China.
  • Zhang Y; Department of Thoracic Surgery, Xuanwu Hospital Capital Medical University, Beijing, China.
  • Cang S; Department of Medical Oncology, Henan Provincial People's Hospital, Zhengzhou, China.
  • Lan Y; Department of Pneumology and Critical Care Medicine Respiratory Division II, Affiliated Hospital of Zunyi Medical University, Zunyi, China.
  • Chen X; Department of Oncology, 900th Hospital of the Joint Logistics Support Force, Fuzhou, China.
  • Liu L; Department of Respiratory Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.
  • Li X; Department of Medical Oncology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
  • Chen J; Department of Lung Cancer Surgery, Tianjin Medical University General Hospital, Tianjin, China.
  • Ma R; Medical Oncology Department of Thoracic Cancer, Liaoning Cancer Hospital & Institute, Shenyang, China.
  • Guo Y; Department of Medical Oncology, Henan University of Science and Technology First Affiliated Hospital, Luoyang, China.
  • Sun P; Oncology Department Two, Qindao University Medical College Affiliated Yantai Yuhuangding Hospital, Yantai, China.
  • Tian P; Department of Respiratory and Critical Care Medicine, West China Hospital of Sichuan University, Chengdu, China.
  • Pan Y; Department of Medical Oncology, Anhui Provincial Hospital, Hefei, China.
  • Liu Z; Department of Medical Oncology, Beijing Chest Hospital, Capital Medical University, Beijing, China.
  • Cao P; Department of Oncology, Third Xiangya Hospital, Central South University, Changsha, China.
  • Ding L; Betta Pharmaceuticals, Hangzhou, China.
  • Wang Y; Betta Pharmaceuticals, Hangzhou, China.
  • Yuan X; Betta Pharmaceuticals, Hangzhou, China.
  • Wu P; Betta Pharmaceuticals, Hangzhou, China.
Lancet Respir Med ; 11(10): 905-915, 2023 10.
Article em En | MEDLINE | ID: mdl-37244266
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma Pulmonar de Células não Pequenas / Neoplasias Pulmonares Tipo de estudo: Clinical_trials Limite: Adolescent / Adult / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article