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Stabilization of 14-3-3 protein-protein interactions with Fusicoccin-A decreases alpha-synuclein dependent cell-autonomous death in neuronal and mouse models.
Vinueza-Gavilanes, Rodrigo; Bravo-González, Jorge Juan; Basurco, Leyre; Boncristiani, Chiara; Fernández-Irigoyen, Joaquín; Santamaría, Enrique; Marcilla, Irene; Pérez-Mediavilla, Alberto; Luquin, María Rosario; Vales, Africa; González-Aseguinolaza, Gloria; Aymerich, María Soledad; Aragón, Tomás; Arrasate, Montserrat.
Afiliação
  • Vinueza-Gavilanes R; Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain. Electronic address: rvinueza@unav.es.
  • Bravo-González JJ; Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain. Electronic address: jbravog@unav.es.
  • Basurco L; Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain; Biochemistry and Genetics Department, School of Sciences, University of Navarra, Pamplona, Spain. Electronic address: lbasurco@alumni.unav.es.
  • Boncristiani C; Department of Life Sciences, Università degli Studi di Trieste, Trieste, Italy. Electronic address: chiara.boncristiani@phd.units.it.
  • Fernández-Irigoyen J; Proteored-Institute of Health Carlos III (ISCIII), Clinical Neuroproteomics Unit, Navarrabiomed, Navarra Health Department, Public University of Navarra, Pamplona, Spain; IdiSNA (Navarra Institute for Health Research), Pamplona, Spain. Electronic address: jfernani@navarra.es.
  • Santamaría E; Proteored-Institute of Health Carlos III (ISCIII), Clinical Neuroproteomics Unit, Navarrabiomed, Navarra Health Department, Public University of Navarra, Pamplona, Spain; IdiSNA (Navarra Institute for Health Research), Pamplona, Spain. Electronic address: enrique.santamaria.martinez@navarra.es.
  • Marcilla I; Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain; IdiSNA (Navarra Institute for Health Research), Pamplona, Spain. Electronic address: imargar@unav.edu.
  • Pérez-Mediavilla A; Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain; Biochemistry and Genetics Department, School of Sciences, University of Navarra, Pamplona, Spain; IdiSNA (Navarra Institute for Health Research), Pamplona, Spai
  • Luquin MR; Department of Neurology, Clínica Universidad de Navarra, University of Navarra, Pamplona, Spain; IdiSNA (Navarra Institute for Health Research), Pamplona, Spain. Electronic address: rluquin@unav.es.
  • Vales A; Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain; IdiSNA (Navarra Institute for Health Research), Pamplona, Spain. Electronic address: avales@unav.es.
  • González-Aseguinolaza G; Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain; IdiSNA (Navarra Institute for Health Research), Pamplona, Spain. Electronic address: ggasegui@unav.es.
  • Aymerich MS; Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain; Biochemistry and Genetics Department, School of Sciences, University of Navarra, Pamplona, Spain; IdiSNA (Navarra Institute for Health Research), Pamplona, Spai
  • Aragón T; Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain; IdiSNA (Navarra Institute for Health Research), Pamplona, Spain. Electronic address: taragon@unav.es.
  • Arrasate M; Gene Therapy and Regulation of Gene Expression Program, Center for Applied Medical Research (CIMA), University of Navarra, Pamplona, Spain; Department of Pathology, Anatomy and Physiology, School of Medicine, University of Navarra, Pamplona, Spain; IdiSNA (Navarra Institute for Health Research), Pam
Neurobiol Dis ; 183: 106166, 2023 07.
Article em En | MEDLINE | ID: mdl-37245833

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alfa-Sinucleína / Sinucleinopatias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Alfa-Sinucleína / Sinucleinopatias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article