Pharmacogenomic-guided dosing of fluoropyrimidines beyond <i>DPYD</i>: time for a polygenic algorithm?

Maslarinou, Anthi; Manolopoulos, Vangelis G; Ragia, Georgia

Pharmacogenomic-guided dosing of fluoropyrimidines beyond DPYD: time for a polygenic algorithm?

Maslarinou, Anthi; Manolopoulos, Vangelis G; Ragia, Georgia.

Afiliação

Maslarinou A; Laboratory of Pharmacology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Manolopoulos VG; Individualised Medicine and Pharmacological Research Solutions Center, Alexandroupolis, Greece.
Ragia G; Laboratory of Pharmacology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.

Front Pharmacol ; 14: 1184523, 2023.

Article em En | MEDLINE | ID: mdl-37256234

Palavras-chave

5-fluorouracil; capecitabine; fluoropyrimidines; pharmacogenomics; polygenic dosing algorithm; precision medicine; tegafur; toxicity

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline / Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Guideline / Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article