Chemoresistance in pancreatic ductal adenocarcinoma: Overcoming resistance to therapy.

Bhoopathi, Praveen; Mannangatti, Padmanabhan; Das, Swadesh K; Fisher, Paul B; Emdad, Luni

Bhoopathi, Praveen; Mannangatti, Padmanabhan; Das, Swadesh K; Fisher, Paul B; Emdad, Luni.

Afiliação

Bhoopathi P; Department of Human and Molecular Genetics, Virginia Commonwealth University, School of Medicine, Richmond, VA, United States; VCU Institute of Molecular Medicine, Richmond, VA, United States.
Mannangatti P; Department of Human and Molecular Genetics, Virginia Commonwealth University, School of Medicine, Richmond, VA, United States; VCU Institute of Molecular Medicine, Richmond, VA, United States.
Das SK; Department of Human and Molecular Genetics, Virginia Commonwealth University, School of Medicine, Richmond, VA, United States; VCU Institute of Molecular Medicine, Richmond, VA, United States; VCU Massey Cancer Center, Virginia Commonwealth University, School of Medicine, Richmond, VA, United States
Fisher PB; Department of Human and Molecular Genetics, Virginia Commonwealth University, School of Medicine, Richmond, VA, United States; VCU Institute of Molecular Medicine, Richmond, VA, United States; VCU Massey Cancer Center, Virginia Commonwealth University, School of Medicine, Richmond, VA, United States
Emdad L; Department of Human and Molecular Genetics, Virginia Commonwealth University, School of Medicine, Richmond, VA, United States; VCU Institute of Molecular Medicine, Richmond, VA, United States; VCU Massey Cancer Center, Virginia Commonwealth University, School of Medicine, Richmond, VA, United States

Adv Cancer Res ; 159: 285-341, 2023.

Article em En | MEDLINE | ID: mdl-37268399

Assuntos

Carcinoma Ductal Pancreático; Neoplasias Pancreáticas; Humanos; Gencitabina; Desoxicitidina/farmacologia; Desoxicitidina/uso terapêutico; Resistencia a Medicamentos Antineoplásicos; Carcinoma Ductal Pancreático/tratamento farmacológico; Carcinoma Ductal Pancreático/genética; Carcinoma Ductal Pancreático/metabolismo; Neoplasias Pancreáticas/tratamento farmacológico; Neoplasias Pancreáticas/metabolismo; Linhagem Celular Tumoral; Microambiente Tumoral; Neoplasias Pancreáticas

Palavras-chave

Autophagy; Chemoresistance; Chemosensitization; EMT; Epithelial to mesenchymal transition; Extra cellular vesicles; Gemcitabine; Metabolism; Microbiome; Microenvironment; Pancreatic cancer; Tumor microenvironment; lncRNA; miRNA

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Carcinoma Ductal Pancreático Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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