In silico induced effect of N-Îµ-lysine acetylation on microtubule stability and subsequent interaction of microtubule-associated proteins.

Rayevsky, Alexey; Bulgakov, Elijah; Sharifi, Mohsen; Samofalova, Dariya; Ozheredov, Daniil; Karpov, Pavel; Pantano, Sergio; Blume, Yaroslav

Rayevsky, Alexey; Bulgakov, Elijah; Sharifi, Mohsen; Samofalova, Dariya; Ozheredov, Daniil; Karpov, Pavel; Pantano, Sergio; Blume, Yaroslav.

Afiliação

Rayevsky A; Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine, Ðyiv, Ukraine.
Bulgakov E; Department of Molecular Modeling, Enamine Ltd., Kyiv, Ukraine.
Sharifi M; Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine, Ðyiv, Ukraine.
Samofalova D; Department of Molecular Modeling, Enamine Ltd., Kyiv, Ukraine.
Ozheredov D; RockGen Therapeutics, Little Rock, Arkansas, USA.
Karpov P; Institute of Food Biotechnology and Genomics, National Academy of Sciences of Ukraine, Ðyiv, Ukraine.
Pantano S; R&D Department, Life Chemicals Inc., Niagara-on-the-Lake, Ontario, Canada.
Blume Y; Institute of High Technologies, Glushkova Ave, Taras Shevchenko National University of Kyiv, Kyiv, Ukraine.

Cell Biol Int ; 47(9): 1547-1557, 2023 Sep.

Article em En | MEDLINE | ID: mdl-37272280

Assuntos

Lisina; Microtúbulos; Animais; Humanos; Lisina/metabolismo; Acetilação; Microtúbulos/metabolismo; Tubulina (Proteína)/metabolismo; Proteínas Associadas aos Microtúbulos/metabolismo; Mamíferos/metabolismo

Palavras-chave

CHARMM36; Gromacs; SIRAH 2.0; acetylation sites; autophagy-related protein; tubulin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Lisina / Microtúbulos Tipo de estudo: Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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