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Effects of fibre-supplemented enteral feeds on bowel function of non-critically ill tube-fed adults: a meta-analysis of randomised controlled trials.
Tay, Valerie Xin Pei; Mohamed Noor, Nur Asyikin; Tan, Lee Boo.
Afiliação
  • Tay VXP; Department of Dietetics, Singapore General Hospital, Outram Road Singapore 169608, Singapore.
  • Mohamed Noor NA; Department of Dietetics, Singapore General Hospital, Outram Road Singapore 169608, Singapore.
  • Tan LB; Department of Dietetics, Singapore General Hospital, Outram Road Singapore 169608, Singapore.
Br J Nutr ; 130(12): 2076-2087, 2023 12 28.
Article em En | MEDLINE | ID: mdl-37272621
ABSTRACT
Diarrhoea is common in enterally fed patients and can impact their nutritional and overall outcomes. This meta-analysis evaluates the potential benefits of fibre-supplemented (FS) feeds on incidence of diarrhoea and stool frequency in non-critically ill tube-fed adults. Databases including PubMed, Embase and CINAHL with full text were searched for randomised controlled trials (RCT) with adults on exclusive tube feeding, published until August 2022. The Cochrane Collaboration's tool was used for quality assessment. Studies with published results on incidence of diarrhoea and stool frequency were analysed using RevMan 5. Thirteen RCT with 847 non-critically ill patients between 20 and 90 years old without diarrhoea at the onset of enteral feeding were included. Study duration ranged from 3 to 35 d. Nine papers investigated the incidence of diarrhoea where intervention group was given FS and control was given non-fibre-supplemented (NFS) enteral feeds. Those receiving FS feeds were significantly less likely to experience diarrhoea as compared with those using NFS feeds (OR 0·44; 95 % CI 0·20, 0·95; P = 0·04; I2 = 71 %). Combined analysis showed no differences in stool frequency in those receiving NFS feeds (SMD 0·32; 95 % CI -0·53, 1·16; P = 0·47; I2 = 90 %). Results should be interpreted with caution due to considerable heterogeneity between study population, assessment tool for diarrhoea, potential conflict of interest and short duration of studies. This meta-analysis shows that FS feeds can reduce the incidence of diarrhoea in non-critically ill adults; however, the effects of stool frequency remain debatable.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nutrição Enteral / Defecação Tipo de estudo: Clinical_trials / Systematic_reviews Limite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nutrição Enteral / Defecação Tipo de estudo: Clinical_trials / Systematic_reviews Limite: Adult / Aged / Aged80 / Humans / Middle aged Idioma: En Ano de publicação: 2023 Tipo de documento: Article