Clinical characteristics of platelet-mediated killing circulating parasite of major human malaria.

Bi, Dewu; Huang, Xiaodong; Lin, Lü; Tang, Xike; Lu, Yuexi; Lan, Zhenxu; Luo, Shunda; Lin, Jianyan; Luo, Xiaocheng

Bi, Dewu; Huang, Xiaodong; Lin, Lü; Tang, Xike; Lu, Yuexi; Lan, Zhenxu; Luo, Shunda; Lin, Jianyan; Luo, Xiaocheng.

Afiliação

Bi D; The Fourth People's Hospital of Nanning, Nanning, China.
Huang X; Guangxi AIDS Clinical Treatment Center (Nanning), Nanning, China.
Lin L; The Fourth People's Hospital of Nanning, Nanning, China.
Tang X; Guangxi AIDS Clinical Treatment Center (Nanning), Nanning, China.
Lu Y; The Fourth People's Hospital of Nanning, Nanning, China.
Lan Z; Guangxi AIDS Clinical Treatment Center (Nanning), Nanning, China.
Luo S; The Fourth People's Hospital of Nanning, Nanning, China.
Lin J; Guangxi AIDS Clinical Treatment Center (Nanning), Nanning, China.
Luo X; The Fourth People's Hospital of Nanning, Nanning, China.

Ann Med ; 55(1): 2221453, 2023 12.

Article em En | MEDLINE | ID: mdl-37310126

HighlightsPlatelets directly attaching to parasitized erythrocytes.Platelets correlated inversely with parasitaemia and duration of parasite clearance.Artemisinin combination therapy was more effective than artemisinin alone.Weakening killing effects may counteract by artemisinin combination therapy.

Assuntos

Artemisininas; Malária; Parasitos; Trombocitopenia; Humanos; Animais; Plaquetas; Estudos Retrospectivos; Malária/tratamento farmacológico

Palavras-chave

Plasmodium; erythrocytes; malaria; parasite killing; platelets

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Parasitos / Trombocitopenia / Artemisininas / Malária Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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