Ocular Posterior Segment Distribution and Pharmacokinetics of Brimonidine After Intravitreal Administration in Guinea Pigs.

Xiang, Aiqun; He, Hong; Yu, Hanyang; Li, Anzhen; Luo, Yanting; Yang, Junming; Zhong, Xingwu

Xiang, Aiqun; He, Hong; Yu, Hanyang; Li, Anzhen; Luo, Yanting; Yang, Junming; Zhong, Xingwu.

Afiliação

Xiang A; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
He H; Hainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Haikou, China.
Yu H; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Li A; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Luo Y; Hainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Haikou, China.
Yang J; Hainan Eye Hospital and Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Haikou, China.
Zhong X; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

J Ocul Pharmacol Ther ; 39(7): 456-462, 2023 09.

Article em En | MEDLINE | ID: mdl-37311153

Assuntos

Miopia; Corpo Vítreo; Cobaias; Animais; Tartarato de Brimonidina; Cromatografia Líquida; Espectrometria de Massas em Tandem/métodos

Palavras-chave

LC-MS/MS; brimonidine; intravitreal administration; pharmacokinetics; tissue distribution

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Corpo Vítreo / Miopia Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Corpo Vítreo / Miopia Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article