Emerging roles of phase separation in plant transcription and chromatin organization.
Curr Opin Plant Biol
; 75: 102387, 2023 10.
Article
em En
| MEDLINE
| ID: mdl-37311366
ABSTRACT
Transcription is a core step in gene expression. Regulation of transcription is achieved at the level of transcription machinery, local chromatin environment as well as higher-order chromatin organization. Our understanding of transcriptional regulation was advanced by recent introduction of transcription and chromatin-associated condensates, which typically arise via phase separation of proteins and nucleic acids. While studies from mammalian cells are unveiling the mechanisms of phase separation in transcription regulation, those in plants further broaden and deepen our understanding of this process. In this review, we discuss recent progress in plants how phase separation operates in RNA-mediated chromatin silencing, transcription activity, and chromatin compartmentalization.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Plantas
/
Cromatina
Limite:
Animals
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article