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Current and Emerging Imaging Techniques for Neurofibromatosis Type 1-Associated Cutaneous Neurofibromas.
Li, Yingjoy; Blakeley, Jaishri O; Ly, Ina; Berman, Yemima; Lau, Jonathan; Wolkenstein, Pierre; Bergqvist, Christina; Jia, Wangcun; Milner, Thomas E; Katta, Nitesh; Durkin, Anthony J; Kennedy, Gordon T; Rowland, Rebecca; Romo, Carlos G; Fleming, Jane; Kelly, Kristen M.
Afiliação
  • Li Y; Department of Dermatology, School of Medicine, University of California, Irvine, California, USA.
  • Blakeley JO; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Ly I; Stephen E. and Catherine Pappas Center for Neuro-Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA.
  • Berman Y; Department of Clinical Genetics, Royal North Shore Hospital, St Leonards, Australia.
  • Lau J; Department of Clinical Genetics, Royal North Shore Hospital, St Leonards, Australia; Sydney Medical School, The University of Sydney, Camperdown, Australia.
  • Wolkenstein P; Faculty of Medicine and Health, Université Paris-Est Créteil Val de Marne, Créteil, France; Department of Dermatology, National Referral Center for Neurofibromatoses, Henri-Mondor Hospital, Assistance Publique-Hôpital Paris (AP-HP), Créteil, France.
  • Bergqvist C; Department of Dermatology, National Referral Center for Neurofibromatoses, Henri-Mondor Hospital, Assistance Publique-Hôpital Paris (AP-HP), Créteil, France.
  • Jia W; Beckman Laser Institute & Medical Clinic, University of California, Irvine, California, USA.
  • Milner TE; Beckman Laser Institute & Medical Clinic, University of California, Irvine, California, USA; Department of Biomedical Engineering, University of California, Irvine, California, USA.
  • Katta N; Beckman Laser Institute & Medical Clinic, University of California, Irvine, California, USA.
  • Durkin AJ; Beckman Laser Institute & Medical Clinic, University of California, Irvine, California, USA; Department of Biomedical Engineering, University of California, Irvine, California, USA.
  • Kennedy GT; Beckman Laser Institute & Medical Clinic, University of California, Irvine, California, USA.
  • Rowland R; Beckman Laser Institute & Medical Clinic, University of California, Irvine, California, USA.
  • Romo CG; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
  • Fleming J; Department of Clinical Genetics, Royal North Shore Hospital, St Leonards, Australia.
  • Kelly KM; Department of Dermatology, School of Medicine, University of California, Irvine, California, USA; Beckman Laser Institute & Medical Clinic, University of California, Irvine, California, USA. Electronic address: kmkelly@hs.uci.edu.
J Invest Dermatol ; 143(8): 1397-1405, 2023 08.
Article em En | MEDLINE | ID: mdl-37330718
ABSTRACT
A consistent set of measurement techniques must be applied to reliably and reproducibly evaluate the efficacy of treatments for cutaneous neurofibromas (cNFs) in people with neurofibromatosis type 1 (NF1). cNFs are neurocutaneous tumors that are the most common tumor in people with NF1 and represent an area of unmet clinical need. This review presents the available data regarding approaches in use or development to identify, measure, and track cNFs, including calipers, digital imaging, and high-frequency ultrasound sonography. We also describe emerging technologies such as spatial frequency domain imaging and the application of imaging modalities such as optical coherence tomography that may enable the detection of early cNFs and prevention of tumor-associated morbidity.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Neurofibromatose 1 / Neurofibroma Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Neurofibromatose 1 / Neurofibroma Tipo de estudo: Diagnostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article