Prevention of the Genotoxic Effects of Doxorubicin with Anthocyanin-Containing Complex from Sorbus aucuparia L. Fruit.
Bull Exp Biol Med
; 175(1): 49-53, 2023 May.
Article
em En
| MEDLINE
| ID: mdl-37338761
ABSTRACT
We studied the effect of an anthocyanin-containing complex from the fruits of S. aucuparia L. on doxorubicin-induced genotoxicity in bone marrow cells of C57BL/6 mice. The complex reduced the genotoxic effect doxorubicin in metaphase plates of bone marrow cells in 24, 48 h, and 10 days after the administration of the cytostatic. The mean number of single fragments and the fraction of cells with gaps and aberrant metaphases also decreased.
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Base de dados:
MEDLINE
Assunto principal:
Sorbus
Limite:
Animals
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article