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DXO gears mRNA with alternative NAD and m7G caps.
Yang, Xiaofei; Cao, Dechang.
Afiliação
  • Yang X; Germplasm Bank of Wild Species, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China.
  • Cao D; Germplasm Bank of Wild Species, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan 650201, China. Electronic address: caodechang@mail.kib.ac.cn.
Trends Plant Sci ; 28(10): 1083-1085, 2023 10.
Article em En | MEDLINE | ID: mdl-37357082
NAD is a noncanonical mRNA cap that challenges our traditional dogma of N7-methylguanosine (m7G)-capped eukaryotic mRNAs. The relationship between NAD and m7G caps has been elusive. Xiao et al. find that the deNADding enzyme DXO promotes maturation of m7G caps, suggesting that DXO fine-tunes the dynamic balance between alternative RNA cap structures.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Capuzes de RNA / NAD Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Capuzes de RNA / NAD Idioma: En Ano de publicação: 2023 Tipo de documento: Article