Non-POU Domain-Containing Octomer-Binding (NONO) protein expression and stability promotes the tumorigenicity and activation of Akt/MAPK/ß-catenin pathways in human breast cancer cells.

Lone, Bilal Ahmad; Siraj, Fouzia; Sharma, Ira; Verma, Shweta; Karna, Shibendra Kumar Lal; Ahmad, Faiz; Nagar, Preeti; Sachidanandan, Chetana; Pokharel, Yuba Raj

Lone, Bilal Ahmad; Siraj, Fouzia; Sharma, Ira; Verma, Shweta; Karna, Shibendra Kumar Lal; Ahmad, Faiz; Nagar, Preeti; Sachidanandan, Chetana; Pokharel, Yuba Raj.

Afiliação

Lone BA; Cancer Biology Laboratory, Faculty of Life Science and Biotechnology, South Asian University, Rajpur Road, Maidangarhi, New Delhi, 110068, India.
Siraj F; National Institute of Pathology, Safdarjung Hospital Campus, Room No.610, 6th Floor, Ansari Nagar, New Delhi, 110029, India.
Sharma I; National Institute of Pathology, Safdarjung Hospital Campus, Room No.610, 6th Floor, Ansari Nagar, New Delhi, 110029, India.
Verma S; CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, 110025, India.
Karna SKL; Academy of Scientific and Innovative Research (AcSIR), Gaziabad, 201002, India.
Ahmad F; Cancer Biology Laboratory, Faculty of Life Science and Biotechnology, South Asian University, Rajpur Road, Maidangarhi, New Delhi, 110068, India.
Nagar P; Cancer Biology Laboratory, Faculty of Life Science and Biotechnology, South Asian University, Rajpur Road, Maidangarhi, New Delhi, 110068, India.
Sachidanandan C; Cancer Biology Laboratory, Faculty of Life Science and Biotechnology, South Asian University, Rajpur Road, Maidangarhi, New Delhi, 110068, India.
Pokharel YR; CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), New Delhi, 110025, India.

Cell Commun Signal ; 21(1): 157, 2023 06 27.

Article em En | MEDLINE | ID: mdl-37370134

Assuntos

Neoplasias da Mama; beta Catenina; Feminino; Humanos; beta Catenina/metabolismo; Neoplasias da Mama/patologia; Linhagem Celular Tumoral; Movimento Celular; Proliferação de Células; Proteínas de Ligação a DNA/metabolismo; Transição Epitelial-Mesenquimal; Regulação Neoplásica da Expressão Gênica; Peptidilprolil Isomerase de Interação com NIMA/metabolismo; Proteínas Proto-Oncogênicas c-akt/metabolismo; Proteínas de Ligação a RNA/genética; Peixe-Zebra/metabolismo; Animais

Palavras-chave

Apoptosis; Breast cancer; Cancer stem cells; MAPK/ß-catenin; Metastasis; NONO; P53; PIN1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Beta Catenina Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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