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Vpx requires active cellular dNTP biosynthesis to effectively counteract the anti-lentivirus activity of SAMHD1 in macrophages.
Bowen, Nicole E; Tao, Sijia; Cho, Young-Jae; Schinazi, Raymond F; Kim, Baek.
Afiliação
  • Bowen NE; Department of Pediatrics, Center for ViroScience and Cure, School of Medicine, Emory University, Atlanta, Georgia, USA.
  • Tao S; Department of Pediatrics, Center for ViroScience and Cure, School of Medicine, Emory University, Atlanta, Georgia, USA.
  • Cho YJ; Department of Pediatrics, Center for ViroScience and Cure, School of Medicine, Emory University, Atlanta, Georgia, USA.
  • Schinazi RF; Department of Pediatrics, Center for ViroScience and Cure, School of Medicine, Emory University, Atlanta, Georgia, USA; Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
  • Kim B; Department of Pediatrics, Center for ViroScience and Cure, School of Medicine, Emory University, Atlanta, Georgia, USA; Children's Healthcare of Atlanta, Atlanta, Georgia, USA. Electronic address: baek.kim@emory.edu.
J Biol Chem ; 299(8): 104984, 2023 08.
Article em En | MEDLINE | ID: mdl-37390988

Texto completo: 1 Base de dados: MEDLINE Assunto principal: HIV-1 / Proteínas Monoméricas de Ligação ao GTP / Proteínas Virais Reguladoras e Acessórias / Proteína 1 com Domínio SAM e Domínio HD / Nucleotídeos Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: HIV-1 / Proteínas Monoméricas de Ligação ao GTP / Proteínas Virais Reguladoras e Acessórias / Proteína 1 com Domínio SAM e Domínio HD / Nucleotídeos Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article