Photoinduced Reductive Dehalogenation of Phenacyl Bromides with Pyridoxal 5'-Phosphate.
Chem Pharm Bull (Tokyo)
; 71(9): 675-677, 2023 Sep 01.
Article
em En
| MEDLINE
| ID: mdl-37394629
ABSTRACT
We describe the photoinduced reductive debromination of phenacyl bromides using pyridoxal 5'-phosphate (PLP). The reaction requires irradiation with cyan or blue light in an anaerobic atmosphere. Mechanistic analysis reveals the formation of the phenacyl radical as an intermediate in the reaction, implying a single electron transfer to phenacyl bromides from a PLP-derived species resulting from excitation by illumination.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Fosfato de Piridoxal
/
Brometos
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article