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Exploring switch II pocket conformation of KRAS(G12D) with mutant-selective monobody inhibitors.
Akkapeddi, Padma; Hattori, Takamitsu; Khan, Imran; Glasser, Eliezra; Koide, Akiko; Ketavarapu, Gayatri; Whaby, Michael; Zuberi, Mariyam; Teng, Kai Wen; Lefler, Julia; Maso, Lorenzo; Bang, Injin; Ostrowski, Michael C; O'Bryan, John P; Koide, Shohei.
Afiliação
  • Akkapeddi P; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016.
  • Hattori T; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016.
  • Khan I; Dertment of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY 10016.
  • Glasser E; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425.
  • Koide A; Ralph H. Johnson VA Medical Center, Charleston, SC 29425.
  • Ketavarapu G; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016.
  • Whaby M; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016.
  • Zuberi M; Department of Medicine, New York University Grossman School of Medicine, New York, NY 10016.
  • Teng KW; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016.
  • Lefler J; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425.
  • Maso L; Ralph H. Johnson VA Medical Center, Charleston, SC 29425.
  • Bang I; Department of Cell and Molecular Pharmacology and Experimental Therapeutics, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425.
  • Ostrowski MC; Ralph H. Johnson VA Medical Center, Charleston, SC 29425.
  • O'Bryan JP; Laura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016.
  • Koide S; Department of Biochemistry and Molecular Biology, Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425.
Proc Natl Acad Sci U S A ; 120(28): e2302485120, 2023 07 11.
Article em En | MEDLINE | ID: mdl-37399416
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Proteínas Proto-Oncogênicas p21(ras) Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Proteínas Proto-Oncogênicas p21(ras) Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article