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Discovery of benzofuran-2-carboxylic acid derivatives as lymphoid tyrosine phosphatase (LYP) inhibitors for cancer immunotherapy.
Liang, Xiao; Zhao, Huajun; Du, Jintong; Li, Xue; Li, Kangshuai; Zhao, Zhongcheng; Bi, Wenchao; Zhang, Xiaotong; Yu, Dian; Zhang, Jian; Fang, Hao; Hou, Xuben.
Afiliação
  • Liang X; Institute of Medicinal Chemistry and Key Laboratory of Chemical Biology of Natural Products (MOE), Cheeloo College of Medicine, School of Pharmaeutical Science, Shandong University, Jinan, Shandong, 250012, China; Department of Pharmacy, Qilu Hospital of Shandong University, Ji'nan, Shandong, 250012
  • Zhao H; Institute of Immunopharmaceutical Sciences, and Key Laboratory of Chemical Biology of Natural Pro ducts (MOE), Cheeloo College of Medicine, School of Pharmaeutical Science, Shandong University, Jinan, Shandong, 250012, China.
  • Du J; Shandong Cancer Hospital and Institute, Shandong First Medical University, Jinan, Shandong, 250117, China.
  • Li X; Institute of Medicinal Chemistry and Key Laboratory of Chemical Biology of Natural Products (MOE), Cheeloo College of Medicine, School of Pharmaeutical Science, Shandong University, Jinan, Shandong, 250012, China.
  • Li K; Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
  • Zhao Z; Institute of Medicinal Chemistry and Key Laboratory of Chemical Biology of Natural Products (MOE), Cheeloo College of Medicine, School of Pharmaeutical Science, Shandong University, Jinan, Shandong, 250012, China.
  • Bi W; Institute of Immunopharmaceutical Sciences, and Key Laboratory of Chemical Biology of Natural Pro ducts (MOE), Cheeloo College of Medicine, School of Pharmaeutical Science, Shandong University, Jinan, Shandong, 250012, China.
  • Zhang X; Institute of Medicinal Chemistry and Key Laboratory of Chemical Biology of Natural Products (MOE), Cheeloo College of Medicine, School of Pharmaeutical Science, Shandong University, Jinan, Shandong, 250012, China.
  • Yu D; Institute of Medicinal Chemistry and Key Laboratory of Chemical Biology of Natural Products (MOE), Cheeloo College of Medicine, School of Pharmaeutical Science, Shandong University, Jinan, Shandong, 250012, China.
  • Zhang J; Institute of Immunopharmaceutical Sciences, and Key Laboratory of Chemical Biology of Natural Pro ducts (MOE), Cheeloo College of Medicine, School of Pharmaeutical Science, Shandong University, Jinan, Shandong, 250012, China.
  • Fang H; Institute of Medicinal Chemistry and Key Laboratory of Chemical Biology of Natural Products (MOE), Cheeloo College of Medicine, School of Pharmaeutical Science, Shandong University, Jinan, Shandong, 250012, China.
  • Hou X; Institute of Medicinal Chemistry and Key Laboratory of Chemical Biology of Natural Products (MOE), Cheeloo College of Medicine, School of Pharmaeutical Science, Shandong University, Jinan, Shandong, 250012, China. Electronic address: hxb@sdu.edu.cn.
Eur J Med Chem ; 258: 115599, 2023 Oct 05.
Article em En | MEDLINE | ID: mdl-37399712
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzofuranos / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzofuranos / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article