Host Factor Nucleophosmin 1 (NPM1/B23) Exerts Antiviral Effects against Chikungunya Virus by Its Interaction with Viral Nonstructural Protein 3.

Pradeep, Parvanendhu; Sivakumar, Krishnankutty Chandrika; Sreekumar, Easwaran

Pradeep, Parvanendhu; Sivakumar, Krishnankutty Chandrika; Sreekumar, Easwaran.

Afiliação

Pradeep P; Molecular Virology Laboratory, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram, India.
Sivakumar KC; Research Centre, University of Kerala, Thiruvananthapuram, India.
Sreekumar E; Bioinformatics Facility, Rajiv Gandhi Centre for Biotechnology (RGCB), Thiruvananthapuram, India.

Microbiol Spectr ; 11(4): e0537122, 2023 08 17.

Article em En | MEDLINE | ID: mdl-37409962

Assuntos

Febre de Chikungunya; Vírus Chikungunya; Animais; Humanos; Vírus Chikungunya/genética; Febre de Chikungunya/metabolismo; Nucleofosmina; Proteínas não Estruturais Virais/metabolismo; Antivirais/farmacologia; Antivirais/uso terapêutico; Replicação Viral; Interferons

Palavras-chave

ADP-ribosylation; CHIKV; NO38; NPM1; alphavirus; nsP3; numatrin; viral macrodomain

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vírus Chikungunya / Febre de Chikungunya Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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