H2O2-driven enzymatic oxyfunctionalization of tertiary C-H bonds.
Chem Commun (Camb)
; 59(60): 9219-9222, 2023 Jul 25.
Article
em En
| MEDLINE
| ID: mdl-37416971
ABSTRACT
Peroxygenase from Agrocybe aegerita catalyses the selective hydroxylation of tertiary C-H bonds, whereby tertiary alcohols, diols, ketols, etc., were obtained in good to high regioselectivity and turnover numbers. This method can also be expanded for late-stage functionalization of drug molecules, which represents a streamlined synthetic method to give access to useful compounds.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Peróxido de Hidrogênio
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article