Phenotypic and functional characterization of subpopulation of Imatinib resistant chronic myeloid leukemia cell line.

Hekmatshoar, Yalda; Karadag Gurel, Aynur; Ozkan, Tulin; Rahbar Saadat, Yalda; Koc, Asli; Karabay, Arzu Zeynep; Bozkurt, Sureyya; Sunguroglu, Asuman

Hekmatshoar, Yalda; Karadag Gurel, Aynur; Ozkan, Tulin; Rahbar Saadat, Yalda; Koc, Asli; Karabay, Arzu Zeynep; Bozkurt, Sureyya; Sunguroglu, Asuman.

Afiliação

Hekmatshoar Y; Department of Medical Biology, School of Medicine, Altinbas University, Istanbul, Turkey; Department of Medical Biology, School of Medicine, Ankara University, Ankara, Turkey. Electronic address: yalda.hekmatshoar@altinbas.edu.tr.
Karadag Gurel A; Department of Medical Biology, School of Medicine, Usak University, Usak, Turkey. Electronic address: aynur.karadag@usak.edu.tr.
Ozkan T; Department of Medical Biology, School of Medicine, Ankara University, Ankara, Turkey.
Rahbar Saadat Y; Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Koc A; Faculty of Pharmacy, Department of Biochemistry, Ankara University, Ankara, Turkey.
Karabay AZ; Faculty of Pharmacy, Department of Biochemistry, Ankara University, Ankara, Turkey.
Bozkurt S; Department of Medical Biology, School of Medicine, Istinye University, Istanbul, Turkey.
Sunguroglu A; Department of Medical Biology, School of Medicine, Ankara University, Ankara, Turkey.

Adv Med Sci ; 68(2): 238-248, 2023 Sep.

Article em En | MEDLINE | ID: mdl-37421850

Assuntos

Leucemia Mielogênica Crônica BCR-ABL Positiva; Inibidores de Proteínas Quinases; Humanos; Mesilato de Imatinib/farmacologia; Mesilato de Imatinib/uso terapêutico; Inibidores de Proteínas Quinases/farmacologia; Inibidores de Proteínas Quinases/uso terapêutico; Resistencia a Medicamentos Antineoplásicos/genética; Células K562; Apoptose; Proteínas de Fusão bcr-abl/genética; Proteínas de Fusão bcr-abl/metabolismo; Proteínas de Fusão bcr-abl/farmacologia; Leucemia Mielogênica Crônica BCR-ABL Positiva/tratamento farmacológico; Leucemia Mielogênica Crônica BCR-ABL Positiva/genética; Leucemia Mielogênica Crônica BCR-ABL Positiva/patologia; Fenótipo

Palavras-chave

Chronic myeloid leukemia; Drug resistance; Epithelialmesenchymal transition; Phenotype switching; Tyrosine kinase inhibitors

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mielogênica Crônica BCR-ABL Positiva / Inibidores de Proteínas Quinases Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google