The topoisomerase II ß -kinase associated with HIV-1 is a potential target for pyridine-bischalcones' anti-HIV-1 activity.

Kammari, Kurumurthy; Devaraya, Kiran; Swain, Sarita; Kondapi, Anand K

Kammari, Kurumurthy; Devaraya, Kiran; Swain, Sarita; Kondapi, Anand K.

Afiliação

Kammari K; Department of Biotechnology & Bioinformatics, School of Life Sciences, University of Hyderabad, India.
Devaraya K; Department of Biotechnology & Bioinformatics, School of Life Sciences, University of Hyderabad, India.
Swain S; Department of Biotechnology & Bioinformatics, School of Life Sciences, University of Hyderabad, India.
Kondapi AK; Department of Biotechnology & Bioinformatics, School of Life Sciences, University of Hyderabad, India. Electronic address: akondapi@uohyd.ac.in.

Eur J Med Chem ; 259: 115623, 2023 Nov 05.

Article em En | MEDLINE | ID: mdl-37473689

Assuntos

Fármacos Anti-HIV; Chalcona; Replicação do DNA; DNA Topoisomerases Tipo II/metabolismo; Piridinas/farmacologia; Piridinas/química; Relação Quantitativa Estrutura-Atividade; Fármacos Anti-HIV/química

Palavras-chave

3D-QSAR; Chalcone; HIV-1; HIV-1-Associated topoisomerase II ß kinase (TopoIIßK(HIV-1)); Pyridine bis-chalcones; p24

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Chalcona / Fármacos Anti-HIV Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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