Case of Extensively Drug-Resistant Shigella sonnei Infection, United States.

Choi, Hosoon; Navarathna, Dhammika H; Harston, Brennon L; Hwang, Munok; Corona, Brandon; San Juan, Ma Rowen; Jinadatha, Chetan

Choi, Hosoon; Navarathna, Dhammika H; Harston, Brennon L; Hwang, Munok; Corona, Brandon; San Juan, Ma Rowen; Jinadatha, Chetan.

Emerg Infect Dis ; 29(8): 1708-1711, 2023 08.

Article em En | MEDLINE | ID: mdl-37486233

RESUMO

We report extensively drug-resistant (XDR) Shigella sonnei infection in an immunocompromised patient in Texas, USA. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry failed to identify XDR Shigella, but whole-genome sequencing accurately characterized the strain. First-line antimicrobials are not effective against emerging XDR Shigella. Fosfomycin, carbapenems, and tigecycline are potential alternatives.

Assuntos

Anti-Infecciosos; Disenteria Bacilar; Shigella; Humanos; Antibacterianos/farmacologia; Antibacterianos/uso terapêutico; Anti-Infecciosos/farmacologia; Disenteria Bacilar/diagnóstico; Disenteria Bacilar/tratamento farmacológico; Disenteria Bacilar/epidemiologia; Testes de Sensibilidade Microbiana; Shigella sonnei/genética; Estados Unidos/epidemiologia

Palavras-chave

MSM; Shigella sonnei; United States; XDR Shigella; antimicrobial resistance; bacteria; enteric infections; extensively drug-resistant Shigella; men who have sex with men; sexually transmitted infections; whole-genome sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Shigella / Disenteria Bacilar / Anti-Infecciosos Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans País como assunto: America do norte Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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