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The solute carrier SPNS2 recruits PI(4,5)P2 to synergistically regulate transport of sphingosine-1-phosphate.
Tang, Haiping; Li, Huanyu; Prakaash, Dheeraj; Pedebos, Conrado; Qiu, Xingyu; Sauer, David B; Khalid, Syma; Duerr, Katharina; Robinson, Carol V.
Afiliação
  • Tang H; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK; Kavli Institute for Nanoscience Discovery, Oxford OX1 3QU, UK.
  • Li H; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Prakaash D; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
  • Pedebos C; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
  • Qiu X; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK; Kavli Institute for Nanoscience Discovery, Oxford OX1 3QU, UK.
  • Sauer DB; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK.
  • Khalid S; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.
  • Duerr K; Centre for Medicines Discovery, Nuffield Department of Medicine, University of Oxford, Oxford OX3 7DQ, UK; OMass Therapeutics, Ltd., Oxford OX4 2GX, UK.
  • Robinson CV; Department of Chemistry, University of Oxford, Oxford OX1 3TA, UK; Kavli Institute for Nanoscience Discovery, Oxford OX1 3QU, UK. Electronic address: carol.robinson@chem.ox.ac.uk.
Mol Cell ; 83(15): 2739-2752.e5, 2023 08 03.
Article em En | MEDLINE | ID: mdl-37499662
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esfingosina / Lisofosfolipídeos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Esfingosina / Lisofosfolipídeos Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article