Physicochemical considerations in the formulation development of silicone elastomer vaginal rings releasing 5-nitroimidazole drugs for the treatment of bacterial vaginosis.

Zhao, Xinyu; Boyd, Peter; Dallal Bashi, Yahya H; McCoy, Clare F; Karl Malcolm, R

Zhao, Xinyu; Boyd, Peter; Dallal Bashi, Yahya H; McCoy, Clare F; Karl Malcolm, R.

Afiliação

Zhao X; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.
Boyd P; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.
Dallal Bashi YH; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.
McCoy CF; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK.
Karl Malcolm R; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. Electronic address: k.malcolm@qub.ac.uk.

Int J Pharm ; 644: 123296, 2023 Sep 25.

Article em En | MEDLINE | ID: mdl-37553058

Assuntos

Dispositivos Anticoncepcionais Femininos; Ornidazol; Vaginose Bacteriana; Feminino; Humanos; Vaginose Bacteriana/tratamento farmacológico; Elastômeros de Silicone; Preparações de Ação Retardada/uso terapêutico; Administração Intravaginal; Metronidazol; Antibacterianos; Tinidazol; Ornidazol/uso terapêutico

Palavras-chave

Bacterial vaginosis; Intravaginal ring; Multipurpose prevention technologies (MPT); Sustained release

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ornidazol / Vaginose Bacteriana / Dispositivos Anticoncepcionais Femininos Limite: Female / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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