Characterization of Mycobacterium abscessus colony-biofilms based on bi-dimensional images.
Antimicrob Agents Chemother
; 67(9): e0040223, 2023 09 19.
Article
em En
| MEDLINE
| ID: mdl-37565746
ABSTRACT
Mycobacterium abscessus biofilm aggregates have been shown in the lungs of cystic fibrosis patients and are often tolerant to drugs. Herein, we analyzed bi-dimensional images of either fluorescent or Congo red-stained M. abscessus colony-biofilms grown on a membrane to monitor growth and shape of M. abscessus smooth and rough variants. These colony-biofilms responded differently to rifabutin and bedaquiline, thus highlighting the importance of the morphotype to properly address antibiotic treatment in patients with biofilm-related infections.
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Texto completo:
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Base de dados:
MEDLINE
Assunto principal:
Mycobacterium abscessus
/
Infecções por Mycobacterium não Tuberculosas
Limite:
Humans
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article