CC5 and CC8, Two Disintegrin Isoforms from <i>Cerastes cerastes</i> Snake Venom Decreased Inflammation Response In Vitro and In Vivo.

Morjen, Maram; Zakraoui, Ons; Abdelkafi-Koubaa, Zaineb; Srairi-Abid, Najet; Marrakchi, Naziha; Essafi-Benkhadir, Khadija; Jebali, Jed

CC5 and CC8, Two Disintegrin Isoforms from Cerastes cerastes Snake Venom Decreased Inflammation Response In Vitro and In Vivo.

Morjen, Maram; Zakraoui, Ons; Abdelkafi-Koubaa, Zaineb; Srairi-Abid, Najet; Marrakchi, Naziha; Essafi-Benkhadir, Khadija; Jebali, Jed.

Afiliação

Morjen M; Laboratory of Biomolecules, Venoms and Theranostic Applications, LR20IPT01, Pasteur Institute of Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Zakraoui O; Laboratory of Molecular Epidemiology and Experimental Pathology, LR16IPT04, Pasteur Institute of Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Abdelkafi-Koubaa Z; Laboratory of Biomolecules, Venoms and Theranostic Applications, LR20IPT01, Pasteur Institute of Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Srairi-Abid N; Research Laboratory of Precision Medicine/Personalized Medicine and Oncology Investigation, LR21SP01, Salah Azaiez Institute, University of Tunis El Manar, Tunis 1007, Tunisia.
Marrakchi N; Laboratory of Biomolecules, Venoms and Theranostic Applications, LR20IPT01, Pasteur Institute of Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Essafi-Benkhadir K; Laboratory of Biomolecules, Venoms and Theranostic Applications, LR20IPT01, Pasteur Institute of Tunis, University of Tunis El Manar, Tunis 1002, Tunisia.
Jebali J; Medicine School of Tunis, University of Tunis El Manar, 15 Djebel Lakhdhar Street, La Rabta, Tunis 1007, Tunisia.

Int J Mol Sci ; 24(15)2023 Aug 04.

Article em En | MEDLINE | ID: mdl-37569801

Assuntos

Desintegrinas; Viperidae; Ratos; Camundongos; Humanos; Animais; Desintegrinas/farmacologia; Lipopolissacarídeos/toxicidade; Viperidae/metabolismo; Venenos de Serpentes/farmacologia; NF-kappa B/metabolismo; Inflamação/tratamento farmacológico; Citocinas/metabolismo; Isoformas de Proteínas; Anti-Inflamatórios/farmacologia; Anti-Inflamatórios/uso terapêutico; Células RAW 264.7

Palavras-chave

cytokines; disintegrin; inflammation; signaling pathways; snake venom

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Viperidae / Desintegrinas Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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