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Spinal cord and brain concentrations of riluzole after oral and intrathecal administration: A potential new treatment route for amyotrophic lateral sclerosis.
Keifer, Orion P; Gutierrez, Juanmarco; Butt, Mark T; Cramer, Sarah D; Bartus, Raymond; Tansey, Malu; Deaver, Daniel; Betourne, Alexandre; Boulis, Nicholas M.
Afiliação
  • Keifer OP; Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, United States of America.
  • Gutierrez J; Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, United States of America.
  • Butt MT; Tox Path Specialists, LLC (a StageBio Company), Frederick, MD, United States of America.
  • Cramer SD; Tox Path Specialists, LLC (a StageBio Company), Frederick, MD, United States of America.
  • Bartus R; RTBioconsultants, San Diego, CA, United States of America.
  • Tansey M; Department of Physiology, Emory University School of Medicine, Atlanta, GA, United States of America.
  • Deaver D; Deaver Non-Clinical Drug Development Consulting, LLC, Franklin, MA, United States of America.
  • Betourne A; Above and Beyond NB LLC, Atlanta, GA, United States of America.
  • Boulis NM; Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, United States of America.
PLoS One ; 18(8): e0277718, 2023.
Article em En | MEDLINE | ID: mdl-37607205

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos / Esclerose Lateral Amiotrófica Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos / Esclerose Lateral Amiotrófica Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article