Deletion of <i>Gtf2i</i> via Systemic Administration of AAV-PHP.eB Virus Increases Social Behavior in a Mouse Model of a Neurodevelopmental Disorder.

Ophir, Omer; Levy, Gilad; Bar, Ela; Kimchi Feldhorn, Omri; Rokach, May; Elad Sfadia, Galit; Barak, Boaz

Deletion of Gtf2i via Systemic Administration of AAV-PHP.eB Virus Increases Social Behavior in a Mouse Model of a Neurodevelopmental Disorder.

Ophir, Omer; Levy, Gilad; Bar, Ela; Kimchi Feldhorn, Omri; Rokach, May; Elad Sfadia, Galit; Barak, Boaz.

Afiliação

Ophir O; The Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 6997801, Israel.
Levy G; The Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 6997801, Israel.
Bar E; The School of Psychological Sciences, Faculty of Social Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.
Kimchi Feldhorn O; The School of Neurobiology, Biochemistry & Biophysics, Faculty of Life Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.
Rokach M; The Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 6997801, Israel.
Elad Sfadia G; The Sagol School of Neuroscience, Tel Aviv University, Tel Aviv 6997801, Israel.
Barak B; The School of Psychological Sciences, Faculty of Social Sciences, Tel Aviv University, Tel Aviv 6997801, Israel.

Biomedicines ; 11(8)2023 Aug 15.

Article em En | MEDLINE | ID: mdl-37626769

Palavras-chave

Gtf2i; PHP.eB serotype; Williams syndrome (WS); adeno-associated virus (AAV); excitatory neurons; post-natal deletion; social behavior

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article