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Elimination of senescent cells by treatment with Navitoclax/ABT263 reverses whole brain irradiation-induced blood-brain barrier disruption in the mouse brain.
Gulej, Rafal; Nyúl-Tóth, Ádám; Ahire, Chetan; DelFavero, Jordan; Balasubramanian, Priya; Kiss, Tamas; Tarantini, Stefano; Benyo, Zoltan; Pacher, Pal; Csik, Boglarka; Yabluchanskiy, Andriy; Mukli, Peter; Kuan-Celarier, Anna; Krizbai, István A; Campisi, Judith; Sonntag, William E; Csiszar, Anna; Ungvari, Zoltan.
Afiliação
  • Gulej R; Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Nyúl-Tóth Á; Oklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Ahire C; International Training Program in Geroscience, Doctoral School of Basic and Translational Medicine/Department of Public Health, Semmelweis University, Budapest, Hungary.
  • DelFavero J; Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Balasubramanian P; Oklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Kiss T; International Training Program in Geroscience, Doctoral School of Basic and Translational Medicine/Department of Public Health, Semmelweis University, Budapest, Hungary.
  • Tarantini S; International Training Program in Geroscience, Institute of Biophysics, Biological Research Centre, Eötvös Loránd Research Network, Szeged, Hungary.
  • Benyo Z; Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Pacher P; Oklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Csik B; Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Yabluchanskiy A; Oklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Mukli P; Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Kuan-Celarier A; Oklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Krizbai IA; Stephenson Cancer Center, University of Oklahoma, Oklahoma City, OK, USA.
  • Campisi J; Vascular Cognitive Impairment, Neurodegeneration and Healthy Brain Aging Program, Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Sonntag WE; Oklahoma Center for Geroscience and Healthy Brain Aging, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
  • Csiszar A; International Training Program in Geroscience, First Department of Pediatrics, Semmelweis University, Budapest, Hungary.
  • Ungvari Z; Eötvös Loránd Research Network and Semmelweis University (ELKH-SE) Cerebrovascular and Neurocognitive Disorders Research Group, Budapest, Hungary.
Geroscience ; 45(5): 2983-3002, 2023 10.
Article em En | MEDLINE | ID: mdl-37642933
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Células Endoteliais Tipo de estudo: Guideline / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Barreira Hematoencefálica / Células Endoteliais Tipo de estudo: Guideline / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article