Integrating Liquification of the Gelated Tumor Interstitium around Nanomedicines with Biconditional GD2-Targeting for Precise and Safe Chemotherapy.

Xue, Weili; Lin, Xiaowei; Xu, Liangbo; Trital, Ashish; He, Yi; Tang, Guping; Bai, Hongzhen; Chen, Shengfu

Xue, Weili; Lin, Xiaowei; Xu, Liangbo; Trital, Ashish; He, Yi; Tang, Guping; Bai, Hongzhen; Chen, Shengfu.

Afiliação

Xue W; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang, 310027, China.
Lin X; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang, 310027, China.
Xu L; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang, 310027, China.
Trital A; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang, 310027, China.
He Y; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang, 310027, China.
Tang G; Department of Chemistry, Zhejiang University, Hangzhou, 310028, P. R. China.
Bai H; Department of Chemistry, Zhejiang University, Hangzhou, 310028, P. R. China.
Chen S; Key Laboratory of Biomass Chemical Engineering of Ministry of Education and Zhejiang Key Laboratory of Smart Biomaterials, College of Chemical and Biological Engineering, Zhejiang University, Hangzhou, Zhejiang, 310027, China.

Adv Mater ; 35(49): e2304594, 2023 Dec.

Article em En | MEDLINE | ID: mdl-37651555

Assuntos

Nanomedicina; Neoplasias; Camundongos; Animais; Neoplasias/tratamento farmacológico; Neoplasias/patologia; Doxorrubicina/farmacologia; Doxorrubicina/uso terapêutico; Polissacarídeos; Microambiente Tumoral

Palavras-chave

GD2 targeting; biconditional active targeting; nanomedicine; quick tumor penetration; tumor interstitium liquifying

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanomedicina / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nanomedicina / Neoplasias Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article