Homologous platelet gel on radiation-induced dermatitis in a patient receiving head and neck radiotherapy plus cetuximab: A case report.
Medicine (Baltimore)
; 102(34): e34779, 2023 Aug 25.
Article
em En
| MEDLINE
| ID: mdl-37653754
ABSTRACT
INTRODUCTION:
Acute radiodermatitis is a significant complication of cancer radiotherapy, and platelet-based therapies are emerging as potential new treatments. MAIN SYMPTOMS AND IMPORTANT CLINICALFINDINGS:
In this report, we present the case of a patient with head and neck cancer undergoing radiotherapy combined with the monoclonal antibody cetuximab. After 4 weeks of this treatment, the patient developed cutaneous radiation dermatitis. Despite receiving standard treatment with corticosteroids and emollient cream, the lesion did not improve. MAIN DIAGNOSIS cutaneous radiation dermatitis on head and neck cancer patient. THERAPEUTICINTERVENTIONS:
Topical application of platelet gel was initiated on the wound. From the second week of radiotherapy to the 4th week, homologous platelet-rich plasma was applied on the dermatitis using a bandage, 4 times a day.OUTCOMES:
The topical treatment with homologous platelet gel resulted in complete healing of the radiodermatitis, including restoration of the epidermis, reepithelialization, and reduction in associated pain.CONCLUSION:
homologous platelet gel might be an alternative to standard treatment of radiation dermatitis.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Radiodermite
/
Terapias Complementares
/
Neoplasias Orofaríngeas
/
Cetuximab
/
Antineoplásicos Imunológicos
/
Carcinoma de Células Escamosas de Cabeça e Pescoço
Tipo de estudo:
Etiology_studies
Limite:
Aged
/
Humans
/
Male
Idioma:
En
Ano de publicação:
2023
Tipo de documento:
Article