Euchronin A-F isolated from the Arnebia euchroma (Royle) Johnst. and their anti-proliferative activities in vitro.
J Nat Med
; 78(1): 33-41, 2024 Jan.
Article
em En
| MEDLINE
| ID: mdl-37658159
ABSTRACT
Six new naphthoquinones, euchronin A-F (1-6) and nine known naphthoquinones (7-15), were isolated from the roots of Arnebia euchroma (Royle) Johnst. The structures of the new compounds were confirmed by extensive spectroscopic analyses, including UV, IR, HR-ESI-MS, 1D and 2D NMR. In the present study, we estimated the anti-proliferative activities of these compounds with HaCaT cells. The results indicated that compounds 2 and 4 showed strong anti-proliferative activities at 25 µM, with relative viability at 38.83% and 68.44%, respectively.
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Base de dados:
MEDLINE
Assunto principal:
Naftoquinonas
/
Boraginaceae
Idioma:
En
Ano de publicação:
2024
Tipo de documento:
Article