Metabolic signature and proteasome activity controls synovial migration of CDC42hiCD14+ cells in rheumatoid arthritis.

Malmhäll-Bah, Eric; Andersson, Karin M E; Erlandsson, Malin C; Silfverswärd, Sofia T; Pullerits, Rille; Bokarewa, Maria I

Metabolic signature and proteasome activity controls synovial migration of CDC42^hiCD14⁺ cells in rheumatoid arthritis.

Malmhäll-Bah, Eric; Andersson, Karin M E; Erlandsson, Malin C; Silfverswärd, Sofia T; Pullerits, Rille; Bokarewa, Maria I.

Afiliação

Malmhäll-Bah E; Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Andersson KME; Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Erlandsson MC; Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Silfverswärd ST; Rheumatology Clinic, Sahlgrenska University Hospital, Gothenburg, Sweden.
Pullerits R; Department of Rheumatology and Inflammation Research, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Bokarewa MI; Rheumatology Clinic, Sahlgrenska University Hospital, Gothenburg, Sweden.

Front Immunol ; 14: 1187093, 2023.

Article em En | MEDLINE | ID: mdl-37662900

Assuntos

Artrite Reumatoide; Complexo de Endopeptidases do Proteassoma; Animais; Camundongos; Homeostase; Proteínas rho de Ligação ao GTP; Inflamação; Citocinas

Palavras-chave

CD14+ cells; Rho-GTPases; arthritis; oxidative phosphorylation; proteasome; synovia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Complexo de Endopeptidases do Proteassoma Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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