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Emotion regulation during encoding reduces negative and enhances neutral mnemonic discrimination in individuals with depressive symptoms.
Hayes, Brandon K; Harikumar, Amritha; Ferguson, Lorena A; Dicker, Eva E; Denny, Bryan T; Leal, Stephanie L.
Afiliação
  • Hayes BK; Department of Psychological Sciences, Rice University, 6100 Main St. Houston TX 77005, United States.
  • Harikumar A; Department of Psychological Sciences, Rice University, 6100 Main St. Houston TX 77005, United States.
  • Ferguson LA; Department of Psychological Sciences, Rice University, 6100 Main St. Houston TX 77005, United States.
  • Dicker EE; Department of Psychological Sciences, Rice University, 6100 Main St. Houston TX 77005, United States.
  • Denny BT; Department of Psychological Sciences, Rice University, 6100 Main St. Houston TX 77005, United States.
  • Leal SL; Department of Psychological Sciences, Rice University, 6100 Main St. Houston TX 77005, United States. Electronic address: stephanieleal@rice.edu.
Neurobiol Learn Mem ; 205: 107824, 2023 Nov.
Article em En | MEDLINE | ID: mdl-37673391
Individuals with depression exhibit dysfunctional emotion regulation, general episodic memory deficits, and a negativity bias, where negative experiences are better remembered. Recent work suggests that the negativity bias in depression may be driven by enhanced mnemonic discrimination, a memory measure that relies on hippocampal pattern separation - a computation that processes experiences with overlapping features as unique. Previously, we found that individuals with depressive symptoms show enhanced negative and impaired neutral mnemonic discrimination. The current study aimed to investigate emotion regulation as an approach toward modifying memory encoding of negative and neutral events in individuals with depressive symptoms. Here we show that applying psychological distancing (a cognitive reappraisal strategy characterized by taking a third-person perspective toward negative events) during encoding was associated with reduced negative and enhanced neutral mnemonic discrimination during retrieval in individuals with depressive symptoms. These results suggest that applying emotion regulation techniques during encoding may provide an effective approach toward altering dysfunctional memory in those with depressive symptoms. Given that pharmacological treatments often fail to treat depression, emotion regulation provides a powerful and practical approach toward modifying cognitive and emotional processes. Future neuroimaging studies will be important to determine how emotion regulation impacts the neural mechanisms underlying these findings.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Memória Episódica / Regulação Emocional Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Memória Episódica / Regulação Emocional Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article