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Persistence of long-term insulin independence after islet transplantation and two subsequent pregnancies.
Gondek, Sarah; Ogledzinski, Mateusz; Lin, William; Milejczyk, Kamila; Juengel, Braden; Potter, Lisa; Bachul, Piotr J; Basto, Lindsay; Perea, Laurencia; Wang, Ling-Jia; Tibudan, Martin; Witkowska, Zuzanna; Barth, Rolf; Fung, John; Witkowski, Piotr.
Afiliação
  • Gondek S; The Transplantation Institute, University of Chicago, USA.
  • Ogledzinski M; The Transplantation Institute, University of Chicago, USA.
  • Lin W; The Transplantation Institute, University of Chicago, USA.
  • Milejczyk K; The Transplantation Institute, University of Chicago, USA.
  • Juengel B; The Transplantation Institute, University of Chicago, USA.
  • Potter L; The Transplantation Institute, University of Chicago, USA.
  • Bachul PJ; The Transplantation Institute, University of Chicago, USA.
  • Basto L; The Transplantation Institute, University of Chicago, USA.
  • Perea L; The Transplantation Institute, University of Chicago, USA.
  • Wang LJ; The Transplantation Institute, University of Chicago, USA.
  • Tibudan M; The Transplantation Institute, University of Chicago, USA.
  • Witkowska Z; The Transplantation Institute, University of Chicago, USA.
  • Barth R; The Transplantation Institute, University of Chicago, USA.
  • Fung J; The Transplantation Institute, University of Chicago, USA.
  • Witkowski P; The Transplantation Institute, University of Chicago, USA.
Eur J Transl Clin Med ; 6(1): 9-13, 2023.
Article em En | MEDLINE | ID: mdl-37693941
ABSTRACT
Pregnancy increases metabolic demand for insulin and may lead to the exhaustion of intraportally transplanted islets and post-gestational hyperglycemia. To prevent these complications, we implemented preemptive insulin supplementation during two subsequent pregnancies in an insulin-independent islet transplant recipient. This strategy resulted in optimal blood glucose control during the pregnancies, the preservation of the optimal islet graft function and the postpartum maintenance of long-term insulin independence.
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2023 Tipo de documento: Article