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Gene regulation analysis of patient-derived iPSCs and its CRISPR-corrected control provides a new tool for studying perturbations of ELMOD3 c.512A>G mutation during the development of inherited hearing loss.
Liu, Xianlin; Wen, Jie; Liu, Xuezhong; Chen, Anhai; Li, Sijun; Liu, Jing; Sun, Jie; Gong, Wei; Kang, Xiaoming; Feng, Zhili; He, Chufeng; Mei, Lingyun; Ling, Jie; Feng, Yong.
Afiliação
  • Liu X; Department of Otolaryngology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Wen J; Key Laboratory of Otolaryngology Major Disease Research of Hunan Province, Changsha, Hunan, China.
  • Liu X; Department of Otolaryngology Head and Neck Surgery, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
  • Chen A; Institute of Otolaryngology Head and Neck Surgery, University of South China, Changsha, Hunan, China.
  • Li S; Department of Otolaryngology, University of Miami Miller School of Medicine, Miami, FL, United States of America.
  • Liu J; Department of Otolaryngology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Sun J; Key Laboratory of Otolaryngology Major Disease Research of Hunan Province, Changsha, Hunan, China.
  • Gong W; Department of Otolaryngology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • Kang X; Key Laboratory of Otolaryngology Major Disease Research of Hunan Province, Changsha, Hunan, China.
  • Feng Z; Department of Otolaryngology, Xiangya Hospital, Central South University, Changsha, Hunan, China.
  • He C; Key Laboratory of Otolaryngology Major Disease Research of Hunan Province, Changsha, Hunan, China.
  • Mei L; Department of Otolaryngology Head and Neck Surgery, The Eighth Affiliated Hospital, Sun Yat-sen University, Futian District, Shenzhen, China.
  • Ling J; Department of Otolaryngology Head and Neck Surgery, The Affiliated Changsha Central Hospital, Hengyang Medical School, University of South China, Changsha, Hunan, China.
  • Feng Y; Institute of Otolaryngology Head and Neck Surgery, University of South China, Changsha, Hunan, China.
PLoS One ; 18(9): e0288640, 2023.
Article em En | MEDLINE | ID: mdl-37708136
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Surdez / Células-Tronco Pluripotentes Induzidas / Perda Auditiva Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Surdez / Células-Tronco Pluripotentes Induzidas / Perda Auditiva Limite: Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article