Characterization of norbelladine synthase and noroxomaritidine/norcraugsodine reductase reveals a novel catalytic route for the biosynthesis of Amaryllidaceae alkaloids including the Alzheimer's drug galanthamine.

Majhi, Bharat Bhusan; Gélinas, Sarah-Eve; Mérindol, Natacha; Ricard, Simon; Desgagné-Penix, Isabel

Majhi, Bharat Bhusan; Gélinas, Sarah-Eve; Mérindol, Natacha; Ricard, Simon; Desgagné-Penix, Isabel.

Afiliação

Majhi BB; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, QC, Canada.
Gélinas SE; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, QC, Canada.
Mérindol N; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, QC, Canada.
Ricard S; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, QC, Canada.
Desgagné-Penix I; Department of Chemistry, Biochemistry and Physics, Université du Québec à Trois-Rivières, Trois-Rivières, Québec, QC, Canada.

Front Plant Sci ; 14: 1231809, 2023.

Article em En | MEDLINE | ID: mdl-37711303

Palavras-chave

Amaryllidaceae alkaloids; Leucojum aestivum; Narcissus papyraceus; enzyme activity; norbelladine synthase; noroxomaritidine/norcraugsodine reductase

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article

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Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2023 Tipo de documento: Article