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Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer's disease pathogenesis.
Pomeshchik, Yuriy; Velasquez, Erika; Gil, Jeovanis; Klementieva, Oxana; Gidlöf, Ritha; Sydoff, Marie; Bagnoli, Silvia; Nacmias, Benedetta; Sorbi, Sandro; Westergren-Thorsson, Gunilla; Gouras, Gunnar K; Rezeli, Melinda; Roybon, Laurent.
Afiliação
  • Pomeshchik Y; iPSC Laboratory for CNS Disease Modelling, Department of Experimental Medical Science, BMC D10, Lund University, 22184, Lund, Sweden. yuriy.pomeshchik@med.lu.se.
  • Velasquez E; Strategic Research Area MultiPark, Lund University, 22184, Lund, Sweden. yuriy.pomeshchik@med.lu.se.
  • Gil J; Lund Stem Cell Center, Lund University, 22184, Lund, Sweden. yuriy.pomeshchik@med.lu.se.
  • Klementieva O; iPSC Laboratory for CNS Disease Modelling, Department of Experimental Medical Science, BMC D10, Lund University, 22184, Lund, Sweden.
  • Gidlöf R; Strategic Research Area MultiPark, Lund University, 22184, Lund, Sweden.
  • Sydoff M; Lund Stem Cell Center, Lund University, 22184, Lund, Sweden.
  • Bagnoli S; Clinical Protein Science & Imaging, Department of Biomedical Engineering, BMC D13, Lund University, 22184, Lund, Sweden.
  • Nacmias B; Strategic Research Area MultiPark, Lund University, 22184, Lund, Sweden.
  • Sorbi S; Medical Micro-Spectroscopy, Department of Experimental Medical Science, BMC B10, Lund University, 22184, Lund, Sweden.
  • Westergren-Thorsson G; Lund University BioImaging Centre, Faculty of Medicine, Lund University, 22142, Lund, Sweden.
  • Gouras GK; Lund University BioImaging Centre, Faculty of Medicine, Lund University, 22142, Lund, Sweden.
  • Rezeli M; Laboratorio Di Neurogenetica, Dipartimento Di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino- NEUROFARBA, Università degli Studi di Firenze, 50134, Florence, Italy.
  • Roybon L; IRCCS Fondazione Don Carlo Gnocchi, Florence, Italy.
Acta Neuropathol Commun ; 11(1): 150, 2023 09 15.
Article em En | MEDLINE | ID: mdl-37715247
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas / Doença de Alzheimer Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas / Doença de Alzheimer Tipo de estudo: Etiology_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2023 Tipo de documento: Article